http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2302096-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c24684033fba97d1ad845ce453a57e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-155 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-155 |
| filingDate | 1976-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2302096-A1 |
| titleOfInvention | DERIVATIVES OF |
| abstract | Basic substd. benzoic acid derivs of formula (I): in which Z = amino, NR1R2 or O-R1; R1 and R2 = H, opt. branched, unsatd. or -O or -S-contg. alkyl, cycloalkyl, cycloalkylalkyl, phenylalkyl or heteroalkyl (max 10C) whereby the phenyl ring is opt. substd. with lower alkyl, alkoxy or halogen; R1 and R2 may be linked either by direct C-C-bond or via-O, -N or -S; R2 may also be phenyl, opt. substd. as signified; salts with physiologically-acceptable acids are included. 8 Cpds. (I) are named e.g. 5-amino-2-(4-methylpiperazil-yl)-benzoic acid methyl ester and corresp. ethyl-, n-propyl, benzyl ester etc. The corresp. starting 5-nitro derivs and the 5-amino-2-(4-methylpiperazin-1-yl) benzoic acid of formula are novel cpds. (I) have hypotensive activity with low toxicity and may be used in the treatment of hypertension, esp. essential hyportonia. |
| priorityDate | 1975-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.