http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2285141-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df4e72183c5ee38a234212562dca6570 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-60 |
| filingDate | 1974-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2285141-A1 |
| titleOfInvention | NEW ACETYLSALICYLIC ACID DERIVATIVE, ITS PREPARATION AND THE COMPOSITIONS CONTAINING IT |
| abstract | Acetylsalicylic acid salts of formula (I) are new: (where R1 and R2 are H or 1-4C alkyl or hydroxyalkyl; R3 and R4 are H or 1-4C alkyl, or CR3R4 is a 5- or 6-membered satd. ring, or one of R3 and R4 and one of R1 and R2 together complete a 5- or 6-membered heterocyclic ring; R5 and R6 are H or 1-4C alkyl or hydroxyalkyl; n =0 or 1). Cpds. (I) have the same anti-inflammatory analgesic and antipyretic activity as acetylsalicylic acid (II), while having a higher water-solubility and a lower acid strength, and having the same acute toxicity, they can be administered by injection and are well tolerated by the veins and muscles. Cpds (I) can be prepd. by reacting (II) with R1R2N-(CH2)n-CR3R4-CONR5R6, either in an anhydrous organic solvent (e.g. MeOH, EtOH, i-PrOH acetone or dimethoxyethane), or in an aq. medium followed by concn. and freeze-drying. |
| priorityDate | 1974-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.