http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2281357-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J21-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00 |
| filingDate | 1974-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2281357-A1 |
| titleOfInvention | NEW PROCESS FOR PREPARATION OF STEROID SPIROLACTONS |
| abstract | Steroid spirolactones of formula (I): (where R1 is 1-4C linear alkyl, R2 is H or CH3), are prepd. by (1) reacting (II) with (CH3)3S circled positive X circled negative in presence of a base, (2) dehydrogenating the cpd. obtd. (3) treating wtih an alkyl malonate of formula: R4-OCO-CH2-COOR4, (4) treating with a thioalkanoic acid R1COSH, and (5) heating in neutral aq. medium. (R3 is CH3 or C2H5, R4 is 1-4C straight or branched alkyl, X circled negative is Br or I). Cpd. (I, R1=R2=CH3) is a known diuretic (spironolactone) for treating certain cardiac disorders. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03082894-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03082894-A3 |
| priorityDate | 1974-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.