http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2278704-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a760bf307acddb0484017967033de2b0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 1974-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2278704-A1 |
| titleOfInvention | PROCESS FOR PREPARING (20 S) 3B-N-DIMETHYLAMINO 18,20-DIACETOXY (5A) PREGNANE |
| abstract | Iso ferntamidine (I) (prepd. by catalytic reduction of funtumidine is trifluoracetylated to give the O, N-di tri fluoracetyl deriv (II) which is hydrolysed to the 3 alpha-N-trifluoracetyl deriv (III) halogenated with hypoiodite to 3 alpha-N-triflu oroacetamido-18, 20-3xydo (5 alpha-pregnane (V), hydrolysed to give (20R) 3 alpha-amino-18, 20-oxydo (5 alpha) pregnane (VI) and finally oxidatively deaminated to (20R) 3 oxo-18, 20-oxydo-(5 alpha) pregnane (VI) is dimethylated then converted by the Jeger method to 3 alpha-N-dimethylamino-18, 20-diacetoxy (5 alpha) pregnane (VIII) and opt. hydrolysed to the diol. The corresponding -S-stereoisomer can be prepd. by a similar method. |
| priorityDate | 1973-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.