http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2268015-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6751e740e2eddf7b577ffff54bba9855 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-65 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-65 |
| filingDate | 1974-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2268015-A1 |
| titleOfInvention | Bis-(4-hydroxymethyl-5-hydroxy-6-methyl pyrid-3-ylmethyl) disulphide - prepd. from 3-hydroxymethyl-4-methoxymethyl-5-hydroxy-6-methylpyridine |
| abstract | A new prepn. of bis-(4-hydroxymethyl-S-hydroxy-6-methylpyrid-3-ylmethyl)disulphid- e (I), by converting 3-hydroxymethyl-4-methoxymethyl-5-hydroxy-6-methyl-pyridine hydrochloride (II), with SOCl2, into 3-chloromethyl-4-methoxymethyl-5-hydroxy-6-methylpyridine (III) which is converted into bis-(4-oxymethyl-5-hydroxy-6-methyl-pyrid-3-ylmethyl) disulphide (V) either directly by reaction with alkali metal, disulphides, or with xanthogenates, thiocyanates, thioacetates, thiosulphates, alkali metal trithiocarbonates, thiourea or salts or dithiocarbamic acid via the cpds. of formula (IV): (where X is -S.C.OH, -SCN, then hydrolysing (V) in an acid medium to give (I), used in treating neurasthenia, Parkinson's disease, alcoholism etc. Improved yields over known processes using pyridoxal as starting material which requires protective groups introduced in positions 4 and 5. |
| priorityDate | 1974-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.