http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2262977-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c644138f2071b48b5991a1425d8dde0a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-86 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-06 |
| filingDate | 1975-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2262977-A1 |
| titleOfInvention | Xanthinoxidase-inhibitory-hydrazomomethyl-substd.-pentadiene nitriles - prepd. by reacting 3-ethoxy-2-cyano-N-formylacrylamide with acid hydrazide |
| abstract | Substd. 2-hydrazonomethyl-3-hydroxy-4-aza-2,4-pentadiennitriles of formula (I) including their tautomers and salts with (in)organic acids (in which R3 = 4- N,N-dipropylsulphamoyl -phenyl, pyridyl-(3), pyridyl-(4), 1,3,5-triphenylpyrazolyl-(4)-methyl, 1,2,3,6-tetrahydro-2,6-dioxopyrimidinyl-(4), thiazolidinyl-(4), 1- 6-methoxynaphthyl-(2) -ethyl, 1-methyl-1-(4- 1,2,3,4-tetrahydronaphthyl-(1) -phenoxy)-ethyl, (3-trifluoromethyl phenoxy)-(4-chlorophenyl)-methyl 3-acetyl-thiazoliol-inyl-(4) and esp. 1-methyl-1-(4-chlorophenoxy)-ethyl) have xanthinoxidase inhibitory activity and may be used against gout, coronary insufficiency and anti-arrhythmia. Depending on R3, cpds. (I) also have lipid-lowering, uricosuric-, antiphlogistic-, esp. antirheumatic, and liver-protecting activity. (I) are also inters, for other active cpds. such as 4(1H)pyrimidinones, used esp. against gout. |
| priorityDate | 1974-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.