http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2181763-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-0057 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-001 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 |
| filingDate | 1973-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1973-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2181763-A2 |
| titleOfInvention | Pregnano-oxazepine compounds - with cardiovascular activity |
| abstract | Title cpds. of formula (I): (where R1 is H or lower acyl; R2 and R3 are H or acyl; R5 is H or lower acyl; Y is O or H, OR2' in which R2' is H, acyl, alkyl or tetrahydropyranyl; and Z is O, H2 or H, OR4 in which R4 is H or acyl) are prepd. by treating corresp. cpds. of partial formula (II) (where X is halogen or a sulphonyl gp.) with a base in an org. solv. and opt. eliminating ester gps. and/or esterifying free OH gps. with the desired acid. (I) have hypotensive, diuretic and positive inotropic and myotropic action, and increase coronary blood flow and heart minute volume; they are esp. useful in the treatment of cardiac insufficiency. (I) are also useful as inters. for highly active steroid cpds., e.g. batrachotoxin A. |
| priorityDate | 1972-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID426285887 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID10896821 |
Total number of triples: 18.