http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2173693-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e752c83f437681dc056d7e37f070dec3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-72 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-72 |
filingDate | 1972-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1973-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | FR-2173693-A1 |
titleOfInvention | Recovering pure glycofrangulins - from rhamnus frangula by selective solvent extraction |
abstract | Process for recovering glycofrangulins from crude plant material, esp. the dried bark of the alder buckthorn (Rhamnus frangula L.) comprises extracting the material with a solvent mixt. of (i) a 1-3C alcohol and (ii) a 3-6C aliphatic or cyclic oxo and/or oxido cpd.; removing impurities from the extract by adsorption onto an activated polyamide; treating the purified soln. with a non-aqueous, esp. methanolic, soln. of an alkali hydroxide to produce a salt which is then treated with an acid or ion-exchanger, and solvent removed from the final product in the usual manner. Extract is a mild laxative. Process gives a purer product (90-95% consisting of molecules having at least 2 sugar residues bound to emodin) than prior art processes. Extraction solvent has excellent selectivity; most of the impurities (which are foul smelling and cause undesirable side effects) are irreversibly bound to the polyamide, and the process is suitable for large scale operation. |
priorityDate | 1972-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.