http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2162562-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96e0f035b085c0154d7c3e6ac99ca88e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-09 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-09 |
| filingDate | 1972-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1973-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-2162562-A1 |
| titleOfInvention | Pyrrolidinylmethyl benzamide prepn - by reaction of a pyrrolidinylmethylamine with a benzoic acid mixed anhydride |
| abstract | Process for the prepn. of the compounds of formula (I) by the reaction: (I) is known to have antipsychotic properties and also to be useful in the treatment of gastroduodenal ulcers, vertigo, and migraine of digestive origin. The process gives better yields of purer product than the known process described in FR. 1,472,025. The product is sufficiently pure to be used for pharmaceutical purposes after one recrystallisation. Temp. is pref. below 5 degrees C and suitable solvents are benzene and acetone. (II) is prepd by treatment of 2-methoxy-5-sulphamoylbenzoic acid (IV) with ethyl chloroformate (V) in the presence of an HCl acceptor, and is used for the reaction with (III) without purification, other than the elimination of the hydrochloride salt of the base used as acid acceptor. |
| priorityDate | 1971-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.