http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2162268-A1

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-16
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0096
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J21-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0016
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00
filingDate 1971-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1973-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber FR-2162268-A1
titleOfInvention 6-alpha, 17-beta-dihydroxy-13-beta-ethyl-17-alpha - -ethynylgona-4,9,11-triene-3-one - with anti oesterogenic anti-lh and
abstract (A) 6 alpha, 17 beta-dihydroxy-13 beta-ethyl-17 alpha-ethynylgona-4,9, 11-triene-3-one (I) (B) Compounds of formulae (II) (III) where in (II) Z = hydroxyimino; X = O or ethylenedioxy; R' and R2 together represent a double bond between C11 and C12; Y' is OH; Y2 is H; or Z is X is ethylenedioxy; Y' is acetoxy; Y2 is H; R' is Br; R2 is H; or R' and R2 together form a double bond between C11 and C12; in (III) Y is X is O or ethylenedioxy; Z' and Z2 are together hydroxyimino; or Y is oxo; X is ethylenedioxy; Z' and Z2 are together hydroxyimino; or Y is X is ethylenedioxy; Z' and Z2 are together hydroxyimino, acetoxyimino, or O; or Z' is alpha-OH and Z2 is H. (I) has antioestrogenic; pituitary inhibitory and anti-LH activity, and may be used in treatment of e.g. acne, seborrhoea and circulatory disorders associated with menopause. (I) and (II) are intermediates for (I). Suitable dose of (I) is 0.1 to 10 mg/day for adjlts in unit doses of 0.1 to 2mg.
priorityDate 1971-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
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Total number of triples: 22.