| abstract |
Title cpds. are of formula (I): where R1, R2, R3 = H or alkyl, pref. 1-5C; R4, R5 = H, alkyl (pref. 1-5C) or, together with the N atom, form a 5-7 membered heterocycle which may contain further heteroatoms (O, N or S) and may be substd. by alkyl, aryl, amino, aminoalkyl, OH, hydroxyalkyl, anilide or N-substd. amidoalkyl; n = 1-4). The cpds. may be prepd. by a Houben-Hoesch reaction of the appropriate phloroglucinol deriv. with an aminoalkyl nitrile followed by hydrolysis of the ketimine formed. |