abstract |
N-substd. biguanide pamoic acid salts prepn. Cpds. of formula:- (where R1 = H; R2 = phenylethyl or n-butyl or R1 and R2 = CH3) are pref. prepared by reacting 1 mole equiv. of alkaline palmoate with 2 mole equiv. of hydrohalides of N-substd. biguanide, spec. phenformine, metaphormine, or buformine, in aq. medium at ambient temp. and crystallising the ppt. Cpds. have hypoglycaemic activity. |