http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-1604469-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-18 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-16 |
| filingDate | 1968-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1971-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1971-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FR-1604469-A |
| titleOfInvention | Antirheumatic, diuretic, sedative n-substitu- - ted amides |
| abstract | Pharmaceutical compositions containing as active ingredient a compound of formula Y.NH.CO.Ar where Y is benzhydryl, fluoren-9-yl-dibenzon 2,3;6,7 cycloheptadien-5-yl, xanthen-9-yl; Ar = aryl e.g. phenyl, naphthyl or heterocyclic e.g. pyridyl. The compounds are antirheumatic, antiinflammatory, analgesic, diuretic and sedative agents; 40-70% inhibition of mouse writhing at 50-200 mg/kg. orally, 40% reduction in the carrageenan-induced inflammation of the rat foot by 200 mg/kg. orally of N-(xanthen-9-yl) isonicotinamide; 10 mg/kg. orally of the same compound in the rat gives a 50% incease in urine output without significant loss of potassium. Very low toxicity; no deaths after 2000 mg/kg. orally in mice. |
| priorityDate | 1968-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.