http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-1602668-A
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0021 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-02 |
filingDate | 1968-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1971-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1971-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | FR-1602668-A |
titleOfInvention | Ferric complexes of hydrogenated dextrans for - parenteral and/or enteral treatment of iron-deficiency |
abstract | Ferric complexes of hydrogenated dextrans for parenteral and/or enteral treatment of iron-deficiency in human and/or veterinary medicine. Prepared by mixing precipitated, washed and filtered iron hydroxide, in the moist state, with dry hydrogenated dextran and, optionally, citric acid or its alkali metal salts to give a homogeneous mass, basifying this with NaOH soln., heating the stirred mixture until the end-product is water-soluble, cooling the resulting soln., filtering, and treating the filtrate with an ion-exchanger to remove excess NaOH. Teh hydrogenated dextran used pref. has a reducing power (determined by the Samogyi method) of 0.02-3.0 glucose gramme equvs./100 g. Advantages are that the product has low toxicity and is cheap and easy to make (colloidal ferric hydroxide is not needed, dialysis and electrodialysis are not employed, and materials are used in high concns. so that the working volume of the apparatus used is reduced). The optional use of citric acid or its alkali metal salts reduces the heating time required to make the complex water-soluble, improves the physical properties of the soln. obtained and minimise the fall in pH when the product is treated with ion-exchanger to remove excess NaOH. |
priorityDate | 1967-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.