http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FI-884049-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- |
| filingDate | 1988-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4d467b93b7133bf27b44df47fc3f610 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a86564151e1f079b495d28ebae6b194d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d6383d25292cc9d5696968e1e0b93d6 |
| publicationDate | 1989-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | FI-884049-A |
| titleOfInvention | LAKTAMDERIVAT. |
| abstract | The invention relates to pyrido- and azepino(4,3-b)indol- 1-one derivatives having the general formula (I) <IMAGE> where Im is an imidazole group of the formula <IMAGE> or <IMAGE> and R<1> is a hydrogen atom or a group selected from the following: C1-6alkyl, C3-4alkenyl, C3-10alkynyl, C3-7cycloalkyl, C3- 7-cycloalkyl-C1-4alkyl, phenyl or phenyl-C1-3alkyl, phenylmethoxymethyl, phenoxyethyl, phenoxymethyl, -CO2R<5>, -COR<5>, -CONR<5>R<6> or -SO2R<5> (where R<5> and R<6>, which can be identical or different, are each a hydrogen atom, a C1-4alkyl group or C3-7cycloalkyl group, or a phenyl group or phenylC1-4-alkyl group, where the phenyl group has been substituted at will by one or more C1-4alkyl, C1-4alkoxy or hydroxyl groups or by a halogen atom, provided that R<5> is not a hydrogen atom when R<1> is a -CO2R<5> or a -SO2R<5> group); one of the groups R<2>, R<3> and R<4> is a hydrogen atom or a C1-6alkyl, C3-7cycloalkyl, C3-6alkenyl, phenyl or phenyl C1-3alkyl group, and each of the two other groups, which can be identical or different, is a hydrogen atom or a C1-4alkyl group; n is 2 or 3; and the physiologically acceptable salts and solvates thereof. These compounds are effective and selective antagonists of the 5-hydroxytryptamine effect in 5-HT3 receptors and they are of use, for example, in treating psychotic diseases, anxiety feelings and nausea and vomiting. |
| priorityDate | 1987-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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