| abstract |
PROCEDURE FOR OBTAINING PYRIDINE DERIVATIVES, FROM FORMULA (I). IT CONSISTS OF THE REDUCTION REACTION OF A COMPOUND OF FORMULA (II); FOLLOWED BY THE CONDENSATION REACTION OF THE FORMYL COMPOUND OBTAINED WITH NITROALKANE FROM FORMULA O2NCH2W; AND, FINALLY, REDUCTION AND HYDROLYSIS OF THE COMPOUND OBTAINED TO FORM THE COMPOUND OF FORMULA (I), IN WHICH W AND R9 REPRESENT HYDROGEN OR LOWER ALKYL, R2 IS HYDROGEN OR HALOGEN AND R1 AND R3 CAN BE VARIED. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS DUE TO THEIR CARDIOTONIC ACTIVITY. |