| abstract |
METHOD OF OBTAINING 2- (PIRIDIL AND IMIDAZOILIL) -INDOLES. IT CONSISTS OF CONDENSING UNDER WITTIG REACTION CONDITIONS A COMPOUND OF FORMULA (II) WITH AN ILIDE OF A COMPOUND OF FORMULA (III), TO OBTAIN 2- (PYRIDIL AND IMIDAZOLIL) -INDOLES OF FORMULA (I) WHERE AR IS 3-PYRIDYL O 1-IIDAZOLYL; R2 AND R3, INDEPENDENT ARE H, LOWER ALKYL, HALOGEN, TRIFLUORMETHYL, HYDROXY, LOWER ALCOXY, CARBOXY AND OTHERS; A IS ALKYLENE FROM C 3 TO 12, ALKYLENE FROM C 2 TO 12 AND OTHERS; B IS CARBOXY, STERIFIED CARBOXY, CARBAMOYL, HYDROXIMETHYL, CYANE, HYDROXY-CARBAMOYL AND OTHERS. THEY HAVE PHARMACEUTICAL APPLICATIONS FOR THEIR CARDIOVASCULAR EFFECTS. *FORMULA* |