| abstract |
METHOD TO PREPARE TRICYCLIC IMIDAZO DERIVATIVES. IT CONSISTS OF REACTING A COMPOUND OF FORMULA (II) WITH A COMPOUND OF FORMULA H2N-OR8, IN AN INERT SOLVENT, SUCH AS AN ALCOHOL OR A RESPECTIVE MIXTURE WITH WATER, AT A TEMPERATURE BETWEEN AMBIENT AND THE POINT OF BOILING REACTION. , IN THE PRESENCE OF AN ACID ACCEPTING AGENT, TO OBTAIN TRICYCLIC IMIDAZOL DERIVATIVES OF FORMULA (I) WHERE R1 AND R3 MEAN ONE LOWER ALKYL AND THE OTHER H; R2 IS LOWER ALKYL; AND A IS A COMPOUND OF FORMULA (III). THEY HAVE PHARMACEUTICAL APPLICATIONS FOR THE PREVENTION AND CONTROL OF ULCERS. |