| abstract |
PROCEDURE TO PREPARE 2 (1H) -PIRIDONAS. IT CONSISTS OF CONDENSING A FORMULA (II) ALCANONE WITH A DERIVATIVE OF FORMULA (III) ACRYLIC ACID, CARRYING OUT THE TEMPERATURE REACTION BETWEEN 0 AND 100JC, IN THE SINE OF A SOLVENT AND IN THE PRESENCE OF A STRONG BASE, AND THE COMPOUND OBTAINED FROM FORMULA (IV) IS CONDENSED IN A RING TO OBTAIN 2 (1H) -PIRIDONES FROM FORMULA (I) WHERE YOU HAVE A DOUBLE OR SIMPLE LINK BETWEEN TWO CARBON ATOMS; R1, R3 AND R4 ARE H OR A RADICAL METHYL; R2 IS A RADICAL LOWER ALKYL C 1 TO 4; AND IT'S PHENYLUS OR I HAVE. THEY HAVE PHARMACEUTICAL APPLICATIONS AS CARDIOTONIC AGENTS. |