| abstract |
PROCEDURE FOR OBTAINING COMPOUNDS OF FORMULA (I). IT INCLUDES THE REACTION OF AN ALDEHYDE, OF FORMULA (II), WITH A WITTIG REAGENT, OF FORMULA (R7) 3PB-CH2-D-COOHX1C, TO OBTAIN A COMPOUND OF FORMULA (I), IN WHICH X1 REPRESENTS HALOGEN AND B, D, R2, R3, R4 AND R7 CAN BE SEVERAL RADICALS. THE REACTION IS CARRIED OUT IN AN INERT SOLVENT, AT A TEMPERATURE INCLUDING BETWEEN C50JC AND 80JC. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THE TREATMENT OF INFLAMMATIONS, HYPERTENSION, THROMBES, CEREBRAL APOPLEJIA, INFARCTIONS AND ANGINA PEAK. |