http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-8703893-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9049a49bde9ac86eeef57360697387fa |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 |
| filingDate | 1985-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1987-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-8703893-A1 |
| titleOfInvention | PROCEDURE FOR OBTAINING 1- (N - ((S) -ETOXICARBONIL-3-FENILPROFIL) -L-ALANIL) -L-PROLINA. |
| abstract | PROCEDURE FOR OBTAINING THE DERIVATIVE OF L-PROLINE, FROM FORMULA (I). IT INCLUDES THE REACTION OF ETHYL (R) -4-PHENYL-2-HYDROXIBUTILATE WITH P-TOLUENSULFONYL CHLORIDE, IN TOLUENE AS A SOLVENT, UNDER PHASE TRANSFER CONDITIONS, IN THE PRESENCE OF BENZYLTRIETILAMONIUM CHLORIDE AND HYDROXYL; FOLLOWED BY TREATMENT OF (R) -4-PHENYL-2- (P-TOLUENSULFONYLOXI) ETHYL BUTYRATE FORMED WITH L-ALANYL-L-PROLINE, IN TETRAHYDROFURAN, IN THE PRESENCE OF TRIETILAMINE TO OBTAIN THE FORMULA (I) COMPOUND. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THEIR ANTIHYPERTENSIVE PROPERTIES. |
| priorityDate | 1985-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.