| abstract |
PROCEDURE FOR OBTAINING A MIXED BIOLOGICAL PROBE, FROM A PRECURSOR CONSTITUTED BY A FRAGMENT OF OLIGONUCLEOTIDE AND WHOSE PYRIMIDIC AND PURIC BASES ARE REPLACED BY GROUPS OF FORMULA (I) AND (II). IT CONSISTS OF TREATING THE PRECURSOR WITH A MOLAR MIXTURE OF PYRIDINE ALDOXINE IN TETRAMETHYLGUANIDINE, ADDED WITH AMMONIA, OVER ONE NIGHT, EVAPORATING AND TREATING WITH CONCENTRATED AMMONIA FOR 5 HOURS AT 50 HOURS, AND TREATING MEETHER AT EURTILJC 72 WITH LA DURTILJC 72. |