| abstract |
PROCEDURE FOR OBTAINING INDANO DERIVATIVES, OF FORMULA (I), IN WHICH R4 AND R5 REPRESENT HYDROGEN OR LOWER ALKYL; AND RA, R2 AND R3 CAN BE SEVERAL TYPES OF RADICALS. IT CONSISTS OF THE REACTION OF A DERIVATIVE OF INDANO, OF FORMULA (II), WITH A COMPOUND OF FORMULA RA-W, IN WHICH W IS A HYDROXYL GROUP OR A HALOGEN ATOM AND THE OTHER SYMBOLS HAVE THE SAME MEANING AS IN THE FORMULA ( I). THE REACTION IS CARRIED OUT IN AN INERT ORGANIC SOLVENT AT A TEMPERATURE BETWEEN C30JC AND 180JC. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THEIR ANTI-INFLAMMATORY, HYPOTENSIVE, INHIBITOR OF THE SECRETION OF GASTRIC JUICES AND AGAINST ANOXEMIC AND HYPOXIC SYMPTOMS. |