http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-8603702-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f9db723f41b9245df17b048ca637ad2 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate | 1985-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1986-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-8603702-A3 |
| titleOfInvention | PROCEDURE FOR THE OBTAINING OF 1,6-DIHYDRO-2-METHYL-6-OXO (3,4'-BIPIRIDINO) -5-CARBONITRILO. |
| abstract | PROCEDURE FOR OBTAINING 1,6-DIHYDRO-2-METHYL-6-OXO3,4K-BIPYRIDINE-5-CARBONITRILE. IT INCLUDES: A) REACTING THE MALONITRILE OF FORMULA (II) WITH THE 1-ETOXY-2- (4-PYRIDINYL) -ETHYL (METHYL) KETONE OF FORMULA (III), IN AN ORGANIC SOLVENT SUCH AS METHANOL, ETHANOL OR ISOPROPANOL AND AN TEMPERATURE BETWEEN 50JC AND THE REFLUX TEMPERATURE OF THE SOLVENT, TO OBTAIN 1,6-DIHYDRO-2-METHYL-6-OXO3,4K-BIPYRIDINE-5-CARBONITRILE FROM FORMULA (I), B) ISOLATE A (I) BY CHROMATOGRAPHY OR FRACTIONAL CRYSTALIZATION AND C) RECRISTALIZE TO (I) ISOLATED IN A MIXTURE OF DIMETHYLFORMAMIDE AND WATER. IT IS USED IN THERAPEUTICS. |
| priorityDate | 1982-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.