http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-8603186-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b4beef0c137d9094e6918ee382be22f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-1745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-1785 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
| filingDate | 1985-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1986-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-8603186-A1 |
| titleOfInvention | PROCEDURE TO PREPARE 9- (MONOSUBSTITUTED PROPOXIMETIL IN 1-0 OR IN 3-0 OR DI-SUBSTITUTED IN 1.3-0) -PURINES SUBSTITUTED- IN 1.3-0) -PURINES SUBSTITUTED AS ANTIVIRAL AGENTS |
| abstract | PROCEDURE FOR PREPARING 9- (PROPOXIMETHYL MONOSTITUTED IN 1-O IN 3-O OR DISUSTITUTED IN 1,3-O) -PURINES AS ANTIVIRAL AGENTS. CONSISTENT OF: A) REACTING FORMULA COMPOUNDS (XV) WITH R7NH2, WITH 4-DIMETHYLAMINOPYRIDINE AS A CATALYST, HEATING TO 50-200JC DURING 12 TO 48 HOURS, TO OBTAIN FORMULA (I) COMPOUNDS; AND B) ISOLATE A (I) BY CHROMATOGRAPH. BEING: R1 F H, ALKENYL FROM 2 TO 12 C, CYCLOPENTILO AND OTHERS; R2 IS -C (O) NHR7 WHERE R7 IS A 1 TO 12 C ALCOHOLITE; R3 IS H, HALO, THIO, LOWER ALCOHYLTIO OF 1 TO 6 C AND OTHERS; R4 AND R5 FORM A LINK OR R5 WITH R6 ARE A CETO GROUP AND R4 IS H; R6 IS H, HALO, LOWER ALCOXY OF 1 TO 6 C AND OTHERS; W IS HO 1-CARBONYLIMIDAZOLE; AND WA IS 1-CARBONIMIDAZOLE. THEY ARE USED FOR THEIR POWERFUL ANTIVIRAL ACTIVITY AGAINST HERPES SIMPLEX I AND II VIRUSES AND OTHER RELATED VIRUSES, WHEN ADMINISTERED TO HOT OR COLD BLOOD ANIMALS, AND ESPECIALLY TO HUMANS. |
| priorityDate | 1982-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.