| abstract |
METHOD OF PRODUCTION OF STABLE SALTS OF SULFO-ADENOSIL-L-METHIONINE, FROM THE FORMULA SAMENR (O) M (503H) P, IN WHICH SAME REPRESENTS SULFOADENOSIL-L-METHIONINE; R MAY BE SEVERAL RADICALS; M VALE 0 O 1; AND N IS 1.5 WHEN P IS VALUE 2, AND IS 3 WHEN P IS VALUE 1. UNDERSTAND THE ENRICHMENT OF A YEAST WITH SAME; LISTING OF THE CELLS AND RECOVERING A SOLUTION RICH IN SAME; PURIFICATION OF SAID LIPPING THROUGH ULTRAFILTRATION; PRECIPITATION OF SAME WITH AN ACID SUCH AS SULFONIC ACID, OR WITH AN ESTER OF SULFURIC ACID, OR OF DIOCYLSULFOSUCCINIC ACID. FINALLY, SEPARATION OF THE PRECIPITATED PRODUCT, WASHING IT AND VACUUM DRYING. THESE SALTS HAVE PHARMACOLOGICAL APPLICATIONS IN THE PARENTERAL TREATMENT OF AFFECTIONS. |