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filingDate 1984-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1985-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-8602682-A1
titleOfInvention PROCEDURE TO OBTAIN NEW 3-AMINO ACIDS- (1) -BENZAZEPIN-2-ON-1-ALCANICOS
abstract PROCEDURE FOR OBTAINING NEW 3-AMINO-1-BENZAZEPIN-2-ON-ALKANIC ACIDS. IT INCLUDES: A) CONDENSING A COMPOUND OF FORMULA (II). BEING; R2 AND R5, H OR SUPERIOR ALKYL; R3 AND R4, H, LOWER ALEOXY AND OTHERS; R7, HYDROXY, AMINO AND OTHERS; X, 2 H ATOMS, ONE H AND ONE HYDROXY, AND OTHERS; AND B) REDUCTIVELY RENT THE PRODUCT OBTAINED IN (A) WITH A COMPOUND OF FORMULA (III), IN THE PRESENCE OF FORMIC ACID AND COMPLEX METAL HYDRIDES, SUCH AS SODIUM CYANE-BORUM HYDRIDE, AT 80 C AND USING NOBLE METADIUM CATALYSTS, PALE METALS, PLATINUM AND SODIUM ON A BASE OF BARIUM SALT AND RANEY NICKEL. BEING: R1, H, AMINO-ALKYL LOWER ACCYLATED, AND OTHERS; AND R6, HYDROXY, LOWER DIALKYL, AND OTHERS. THEY ARE USED AS INHIBITORS OF THE ANGIOTEUSIN TRANSFORMING ENZYME.
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