http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-8601177-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4f5641f936ef854ef1b54ca1ae8c9e0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 1984-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1985-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-8601177-A1 |
| titleOfInvention | A PROCEDURE FOR THE PREPARATION OF 1-ARYL-2- (4- (4- (3-OXOBUTYL) PHENYL) PIPERAZIN-1-IL) ETHANONES |
| abstract | PROCEDURE FOR THE PREPARATION OF 1-ARIL-2-Y4-4- (3-OXOBUTIL) PHENYLPIPERAZIN-1-ILZETANONES. IT INCLUDES: A) REACTING THE FORMULA COMPOUND (II) IN WHERE Z IS A GROUP THAT IS ELIMINATED WITH HYDROGENOLYSIS WITH A REAGENT AT A TEMPERATURE BETWEEN C5 AND 40JC TO OBTAIN THE FORMULA (III) COMPOUNDS; B) TREAT THE COMPOUNDS OF A) WITH AN EXCESS OF ACETONE AT A TEMPERATURE BETWEEN 20 AND 60JC AND ADD A DILUTED MINERAL ACID TO OBTAIN THE KETONES OF FORMULA (IV); C) TREAT THE DERIVATIVES OF FORMULA (IV) WITH H, OPERATE WITH ALCOHOL AND SHAKE TO OBTAIN THE PRODUCT OF FORMULA (V) THAT BECOMES DERIVATIVES OF FORMULA (VI) WHERE X IS A NUCLEOFUGO GROUP; AND D) SUBSTITUTE THE DERIVATIVES OF C) TO OBTAIN THE COMPOUNDS OF FORMULA (I) WHERE R1 R2 AND R3 ARE H LOWER ALKYL OR OTHERS. THEY ARE ANALGESIC. |
| priorityDate | 1984-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.