http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-8600747-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ab9d67b444f46c08f9fed932c23d5cc5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-40 |
| filingDate | 1985-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1985-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-8600747-A1 |
| titleOfInvention | PROCEDURE FOR OBTAINING 6-FLUORO-1,4-DIHI-DRO-4-OXO-7-PIPERACINOQUINOLIN-3-CARBOXYLIC ACIDS |
| abstract | PROCEDURE FOR OBTAINING 6-FLUORO-1,4-DIHYDRO-4-OXO-7-PIPERACINOQUINOLIN-3-CARBOXYL ACID DERIVATIVES, FROM ITS PHYSIOLOGICALLY COMPATIBLE ACID ADDITION SALTS AND THEIR HYDRATS (I), FORMULA IN WHICH R1 AND R2 MAY BE SEVERAL RADICALS, INCLUDING THE REACTION OF A COMPOUND OF FORMULA (II), WITH DIETHANOLAMINE OR A DIETHANOLAMINE R1-SUBSTITUTE, IN WHICH R1 AND R2 ARE THE SAME AS IN FORMULA (I), R3 IS HYDROGEN OR LOWER ALKYL, AND X IS CHLORINE OR BROMINE; FOLLOWED BY THE TRANSFORMATION INTO ACID CHLORIDE OF THE COMPOUND FORMED; REACTION WITH DIALKYL MALONATE; DECARBOXYLATION BY HEATING IN WATER, IN THE PRESENCE OF P-TOLUENSULPHONIC ACID; REACTION WITH ETHYL O-FORMATE AND AN AMINE OF FORMULA R2NH2; HEATING IN AN ORGANIC SOLVENT, IN THE PRESENCE OF AN ACID ACCEPTOR, AND LATER WITH AQUEOUS ALKALINE SOLUTION. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THEIR ANTIBACTERIAL PROPERTIES. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2049630-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2049631-A1 |
| priorityDate | 1985-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.