| abstract |
PROCEDURE FOR THE PREPARATION OF ANTAGONISTS OF HYDROGEN RECEPTORS OF HISTAMINE, INCLUDES, A) REACTION TO A COMPOUND OF FORMULA (II) WITH A COMPOUND OF FORMULA (III), TO OBTAIN A COMPOUND OF FORMULA (IV) REACT (IV) WITH A COMPOUND OF FORMULA (R1NH2) TO OBTAIN A COMPOUND OF FORMULA (I) AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS. BEING; R1, H, LOWER ALKYL, 2-FLUOROETHYL AND OTHERS; Z, O, S OR METHYLENE; A RADICAL OF FORMULA (VI) OR (VII) AND OTHERS; R5, H, LOWER ALKYL AND OTHERS; R6 AND R7 LOWER ALKYL, LOWER PHENYLALKYL AND OTHERS; M, 0, 1 O 2; N, 2, 3, 4 O 5 and Q 1, 2, 3 O 4. ARE USED AS ANTI-ULCOS. |