http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-8504767-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45c766a07628f960c7c439498d4254d9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 1984-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1985-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-8504767-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF ACIDES 1-AQUIL-6-FLUORO-7- (1-PIPERAZINIL) -4-OXO-1,4-DIHIDROQUINOLIN-3-CARBOXILICO. |
| abstract | PROCEDURE FOR THE PREPARATION OF SUBSTITUTED 1-ALKYL-6-FLUORO-7- (1-PIPERAZINYL) -4-OXO-1,4-DIHYDROQUINOLIN-3-CARBOXYL ACIDS, OF GENERAL FORMULA (I), AND ITS SALTS WITH ORGANIC ACIDS AND PHYSIOLOGICALLY ACCEPTABLE INORGANIC COMPOUNDS, IT INCLUDES THE FOLLOWING STAGES: FIRST, A COMPOUND 3-CHLORO-4-FLUORO- (N-ALKYL) ANILINE WITH ETOXIMETHYLENMALON-ALKYLL-3-CHLORINE-3-OBLONITRILE IS REACTED BY HEATING ) ANILINE-METHYLENE-MALONONITRILE OF GENERAL FORMULA (II); SECOND, SAID GENERAL FORMULA COMPOUND (II) IS SUBMITTED TO THE CONDITIONS OF THE FRIEDEL-CRAFTS CYCLING REACTION, TO OBTAIN THE 1-ALKYL-6-FLUORO-7-CHLORO-4-IMINO-1,4- STRUCTURE DIHYDRO-QUINOLIN-3-CARBONITRILE, OF GENERAL FORMULA (III); AND FINALLY, THE FORMULA COMPOUND (III) IS REACTED WITH PIPERAZINE, TO OBTAIN THE FORMULA COMPOUND (I). |
| priorityDate | 1984-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.