| abstract |
PROCEDURE FOR PREPARING NEW DERIVATIVES OF W-MERCAPTOTROPANAMIDE. CONSISTS IN THE PREPARATION OF COMPOUNDS OF FORMULA (I) IN WHICH R1 REPRESENTS A HYDROGEN ATOM OR OTHERS; R2 A HYDROGEN ATOM, AN ALKYL RADICAL OR OTHERS; R3 A HETEROCYCLIC RADICAL CHOSEN AMONG THIAZOLYL RADICALS OR OTHERS. AN ACID OF FORMULA (II) IS SUBMITTED IN WHICH R1 AND R2 HAVE THE ABOVE MEANINGS, TO THE ACTION OF AN ACID OF FORMULA H2N-R3, IN WHICH R3 HAS THE PREVIOUS VALUE, TO OBTAIN THE FORMULA (I) COMPOUND WHICH ARE SUBMITTED, IF DESIRED, TO THE ACTION OF A BASE OR AN ACID TO FORM SALT. IT HAS PHARMACOLOGICAL PROPERTIES IN THE TREATMENT OF MUSCULAR, JOINT OR NERVOUS ALGIAS AND IN RHEUMATIC AFFECTIONS. |