| abstract |
PROCEDURE FOR THE PREPARATION OF NEW DICHLORATED DERIVATIVES OF THE SERIES 16-BAB-METIL-PERGNANO.CO IS INVOLVED IN PREPARING THE PRODUCTS OF FORMULA (I) IN WHICH IT REPRESENTS A RADICAL TRIMETILSILYLPHENILO, CICLODECILOXIXE 9BAB, 11-DICLORO-16-BAB-METHYL-21-HIDROX IPREGNA-1,4-DIEN-3,20-DIONA IS REACTED WITH A PRODUCT OF FORMULA (II), IN WHICH HAL REPRESENTS AN ATOMO OF HALOGEN AND YR IT HAS THE MEANING INDICATED ABOVE, AND THE EXPECTED PRODUCT IS OBTAINED. HAL PREFERABLY REPRESENTS AN ATOME OF CHLORINE OR JOKE AND THE REACTION IS MADE IN THE PRESENCE OF A BASIC AGENT LIKE PIRIDINE OR COLIDINE. THEY HAVE A PHARMACOLOGICAL APPLICATION ESPECIALLY AS AN ANTI-INFLAMMATORY. |