| abstract |
PROCEDURE FOR THE PREPARATION OF BENZO-HETEROCICLOS, OF GENERAL FORMULA (I), IN WHICH A MEANS A SIMPLE LINK OR THE GROUP -CH2-CH2-; R1 MEANS OH, O-ACILO, CHLORINE OR HYDROGEN; R2 MEANS HYDROGEN, METHYL OR ETHYL; AND R3 MEANS A RADICAL, AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS. CONSISTS OF HYDROGENING A COMPOUND OF FORMULA (II), IN WHICH A AND R2 HAVE THE MEANINGS ALREADY INDICATED; R1 MEANS A BENZYLOXI GROUP; R3 REPRESENTS R3; AND R REPRESENTS HYDROGEN OR BENZYL EVENTUALLY REPLACED. THE HYDROGENATION REACTION IS EFFECTED IN A ROOM TEMPERATURE SOLVENT AND IN THE PRESENCE OF A HYDROGENATION CATALYST, UP TO THE ABSORPTION OF THE CALCULATED QUANTITY OF HYDROGEN. OF APPLICATION IN THE PREPARATION OF MEDICINES BY ITS ANTIMOLITICS AND BRONCOLITICS EFFECTS BRONCOLITICS. |