| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7b1da85d93179550ad9723c50e07466 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-523
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-542 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0283
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0275
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-42 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-116
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate |
1982-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1984-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-8405275-A1 |
| titleOfInvention |
"A PROCEDURE FOR PREPARING AN ORAL VACCINE FOR IMMUNIZATION AGAINST ENTERIC DISEASES". |
| abstract |
METHOD OF PRODUCING AN ATTENUATED ORAL VACCINE FOR IMMUNIZATION AGAINST ENTERIC DISEASES. IT INCLUDES THE OPERATIONS OF: A) PREPARING A LAYER OF ATTENUATED SALMONELLA TYPHI, GALACTOSE WITHOUT EPIMERASE, TREATED BY GENETIC ENGINEERING TO CARRY THE GENETIC DETERMINANTS OF ADDITIONAL PROTECTIVE ANTIGENS, INCLUDING AT LEAST A SHIGELLA STRAIN, SUCH AS S. SONNEI, S. FLEXNENI, S. DY SENTERIAE AND S. BOYDII; B) PAIRING IN A CONJUGATE WAY THE ATTENUATED SALMONELLA TYPHI STRAIN; C) ISOLATE AND PURIFY A RESULTING CLONE EXPRESSED BY THE ANTIGEN OF S. TYPHI AND WHICH ALSO EXPRESSES THE ANTIGEN OF THE SHIGELLA STRAIN; AND D) FORMING AN ORAL VACCINE BY DISPENSING THE GENETICALLY ENGINEERED CLONIC CELLS IN A LIQUID OR SOLID DILUENT, SUCH AS A TABLET OR CAPSULE. |
| priorityDate |
1981-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |