| abstract |
PROCEDURE FOR THE OBTAINING OF 1-PHENYL-2-AMINO CARBONYLINDOL COMPOUNDS AND THEIR ACID ADDITION SALTS, IN FORMULA (I), IN WHICH Z AND R1-R9 MAY BE SEVERAL TYPES OF RADICALS, CONSISTING IN THE REACTION OF COMPOUNDS FORMULA (II), WITH COMPOUNDS OF FORMULA R8NHR9, IN WHICH AND IS A GROUP THAT CAN BE SEPARATED BY AMINOLYSIS AND THE OTHER SYMBOLS HAVE THE SAME MEANING AS IN FORMULA (I). THE REACTION IS EFFECTED IN AN INERT ORGANIC SOLVENT, IN THE PRESENCE OF A BASE, AT A TEMPERATURE INCLUDING BETWEEN 50JC AND 150JC.THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THE TREATMENT OF THE HEART RATE. |