| abstract |
PROCEDURE FOR OBTAINING AMIDE DERIVATIVES FROM NITROBENZOIC ACID AND ITS PHYSIOLOGICALLY COMPATIBLE ACID ADDITION SALTS, OF FORMULA (I), IN WHICH N IS VALUE 1 OR 2 IT MAY ALREADY BE SEVERAL TYPES OF RADICALS. NITROBENZOIC ACID OF FORMULA (II), OR A REACTIVE DERIVATIVE OF THE SAME, WITH POLYAMIDE OF FORMULA H2N-A-NH2, IN WHICH AYN HAVE THE SAME MEANING AS IN FORMULA (I). THE REACTION IS CARRIED OUT IN AN INERT APROTICAL SOLVENT, IN THE PRESENCE OF A CONDENSING AGENT, AT A TEMPERATURE BETWEEN AMBIENT AND 50JC. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS AS RADIOSENSITIZERS, FOR THE TREATMENT OF CANCER. |