| abstract |
PROCEDURE FOR OBTAINING SUBSTITUTED THIAZOLES, OF FORMULA (I), IN WHICH Y IS HYDROGEN, HYDROXIMETHYL OR ALKYL C <1 <- <4; R IS RENT; AND R IS HYDROGEN, METHYL OR ETHYL. IT CONSISTS OF THE REACTION OF A COMPOUND OF FORMULA (I), WITH AN ALKYLAMINE, OF FORMULA HNRR IN AQUEOUS SOLUTION, FORMULAS IN WHICH X IS HALOGEN AND R, R E AND HAVE THE SAME MEANING AS IN FORMULA (I). THE REACTION IS CARRIED OUT AT A TEMPERATURE BETWEEN 160 C AND 180 C FOR ABOUT 20 HOURS. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THE TREATMENT OF HYPERACIDITY AND PEPTIC ULCERS. |