| abstract |
PROCEDURE FOR THE PREPARATION OF ~C-HYDROXY ACIDS. IT CONSISTS IN SUBJECTING TO A FIRST HYDROLYSIS 5-SUBSTITUTED 2,4-OXAZOLIDINDIONONES OF GENERAL FORMULA (I) IN WHICH R IS AN AROMATIC OR ALIPHATIC RESIDUE, SUBSTITUTED OR NOT; NEXT THE CARBAMIL DERIVATIVES OBTAINED ARE SUBJECTED TO A SECOND HYDROLYSIS. THE FIRST HYDROLYSIS CARRIED OUT IS ENZYMATIC STEREO SELECTIVE, USED AS ENZYMATIC ACTIVITY AGENTS, THEY ARE DERIVED FROM CALF LIVER HOMOGENATES OR FROM MICROORGANISMS SUCH AS PSEUDOMONAS, ACHROMOBACTER, CORYNEBACTERIUM AND OTHERS. |