| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e57e640f3741e8eb30468dbbeec66eb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e89a56b2831eef584685b2a10469724 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-545 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 |
| filingDate |
1981-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1982-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-8206533-A1 |
| titleOfInvention |
PROCEDURE FOR PREPARING METHYLATED DERIVATIVES OF CEFALE-XINA |
| abstract |
PROCEDURE FOR OBTAINING METHYLOLATED DERIVATIVES OF CEPHALEXIN FROM FORMULA (I), IN WHICH X IS AN ALKALINE METAL OR THE NITROGEN-CONTAINING CATION OF A BASIC AMINO ACID. IT CONSISTS OF THE REACTION OF AN AQUEOUS SUSPENSION OF CEPHALEXIN WITH A SOLUTION OF FORMALDEHYDE, MIXED BY STRONG AGITATION AND AT A TEMPERATURE OF 5 TO 10 C., FOLLOWED BY THE REACTION OF THE RESULTING MIXTURE WITH A AQUEOUS SOLUTION OF A HYDROID MOLD THALOX BASE OR WITH A SOLUTION OF A BASIC AMINO ACID SUCH AS LYSINE OR ARGININE. THE PRODUCT OBTAINED IS LYOPHILIZED. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS AS ANTIBIOTICS. |
| priorityDate |
1980-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |