| abstract |
PROCEDURE FOR OBTAINING 2-HALOPYRIDINES AND ITS SALTS, ADDITION COMPOUNDS AND PRECURSORS, FROM FORMULA (I), IN WHICH X IS CHLORINE OR BROMINE AND AR IS PHENYL OR SUBSTITUTED PHENYL. IT CONSISTS OF THE REDUCTION REACTION OF A FORMULA COMPOUND (II), IN WHICH AR AND X HAVE SIGNIFICANCE THAT IN FORMULA (I), WITH A SELECTIVE KETONE REDUCING AGENT, SUCH AS SODIUM BOROHIDRIDE OR LITHIUM ALUMINUMHYDRIDE. THE REACTION IS CARRIED OUT IN AN INERT ORGANIC SOLVENT, IN ANHYDROUS MEDIUM. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THEIR ANALGESIC, ANTI-INFLAMMATORY AND SEDATIVE ACTIVITIES. |