http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-8100294-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6696fe035f9fb746b76a7c92d028d77 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 1979-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-8100294-A1 |
| titleOfInvention | ALTERNATIVE PROCEDURE FOR THE SYNTHESIS OF THE ACID 8-ETIL-5-8-DIHIDRO-5-OXO-2 (1-PIPERAZIMIL) -PIRIDO (2-3, D) -PIRIMIDIN-6 (CARBOXILICO) |
| abstract | PROCEDURE FOR OBTAINING 8-ETHYL-5-8-DIHYDRO-5-OXO-2 (1-PIPERAZIMIL) -PYRID (2-3, D) -PYRIMIDIN-6 (CARBOXYL) ACID. IT CONSISTS OF THE FOLLOWING STAGES: 1. REACTION OF 2-HYDROXY-4-AMINOPYRIMIDINE WITH DIETHYL ETHOXIMETHYLENE-MALONATE, OBTAINING THE N- (4- (2-HYDROXY-PYRAMIDINYL) -AMINE-METHYLENE DIETHYLONATE DELLONATE. PREVIOUS PRODUCT OBTAINING 2-HYDROXY-5,8-DIHYDRO-5-OXO-PYRID- (2,3, D) PYRIMIDIN-6-CARBOXYLATE ETHYLATE 3. BROMATION OF THE PREVIOUS PRODUCT OBTAINING 2-BROMINE-5,8-DIHYDRO ETHYL-5-OXO-PYRID (2,3, D) PYRIMIDINE-6-CARBOXYLATE 4. ALKYLATION OF THE AMINO GROUP OF THE PYRIDINE RING OF THE PREVIOUS PRODUCT OBTAINING ETHYL-2-BROMO-5,8-DIHYDRO-5-OXO -PIRIDO- (2,3, D) PYRIMIDIN-6-CARBOXYLATE 5. SUBSTITUTION OF THE BROMINE IN THE PRODUCT OBTAINED IN THE FOURTH PHASE BY 1-PIPERAZIMIL 6. HYDROXYLIS OF THE ESTER GROUP OF THE SUBSTANCE OBTAINED IN THE FIFTH PHASE OBTAINING THE (2- (1-PIPERAZIMIL) -8-ETHYL-5, 8-DIHYDRO-5-OXO-PYRID- (2,3, D) PYRIMIDIN-6-CARBOXYL ACID. D |
| priorityDate | 1979-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.