| abstract |
Process for preparing alkylene-bis-heterocyclyl-biguanides of the general formula (I) ** formula ** where A signifies heterocycles, if necessary substituted, R signifies alkylene and R1, R2 and R3 are the same or different and signify hydrogen , alkyl or aralkyl, optionally substituted, characterized in that alkylene-bis-dicyandiamides of the general formula (II) **formula** where R,R1 and R2 have the meanings indicated above, are reacted with amino-heterocycles of the general formula (III) **formula** where R3 and A have the meanings indicated above, as free compounds or in salt form, optionally in a solvent or diluent, at temperatures between 80 and 200°C. |