http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-483676-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-587 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-38 |
| filingDate | 1979-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-483676-A1 |
| titleOfInvention | A PROCEDURE FOR PREPARING 3-CEFEM-4-CARBOXYL ACID COMPOUNDS DISSTITUTED IN POSITIONS 3 AND 7 |
| abstract | A process to prepare 3-cephem-4-carboxylic acid compounds disubstituted in positions 3 and 7 of formula-01: ** (Formula-01) ** where R1 is amino or a protected amino, R2 is a hydrocarbon group aliphatic, which may have a suitable substituent or substituents, R3 is carboxy or a protected carboxy, and R4 is a 5-membered heteromonocyclic group, containing N, having one or more lower alkenyl groups, provided that R2 is not methyl when R4 is tetrazolyl having a lower alkenyl group, or its pharmaceutically acceptable salts, which process comprises reacting a compound of the formula-02: ** (Formula-02) ** where R3 and R4 are each as have been defined above, or their reactive derivative in the amino group or a salt thereof, with a compound of the formula-03: ** (Formula-03) ** where R1 and R2 are each as defined above or its reactive derivative at the carboxy group, or a salt thereof and, in case necessary, subjecting the resulting compound, where R1 is a protected amino, to an elimination reaction of the amino protecting group, to give a compound, where R1 is amino, and further, if necessary, subjecting the resulting compound, where R2 is a carboxy-lower alcohol protected to a carboxy-protecting group elimination reaction to give a compound, where R 2 is a carboxy-lower alcohol. |
| priorityDate | 1978-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.