http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-480552-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0be8d6cfb14d04522568dd6146ad713a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D521-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 |
| filingDate | 1979-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-480552-A1 |
| titleOfInvention | A PROCEDURE FOR THE PREPARATION OF SUBSTITUTED DIBENCILIC ETHERS. |
| abstract | A process for the preparation of substituted dibenzyl ethers, of the general formula I **(formula-01)** where R represents a phenyl or phenylthio group, and its pharmaceutically acceptable acid addition salts, characterized in that it comprises condensing at a temperature between 20 and 100 ºC, for 6 to 36 hours, in the presence or absence of potassium iodide as catalyst, in a solvent chosen from the group consisting of aromatic hydrocarbon, dimethylformamide, tetrahydrofuran, hexamethyl-phosphoramide, dimethylforide, tetrahydrofuran, hexamethyl dimethyl phosphoramide or sulfoxide and in the presence of an alkali metal dimethyl hydride and in the presence of an alkali metal hydrodide or amido, or in a solvent consisting of an aliphatic alcohol with 3 to 6 carbon atoms in the presence of an alcoholate alkali metal, 1-(2'', 4''-dichlorophenyl)-2(N-imidazolyl-netyl)- ethanol with a halobenzyl of the formula V **(formula-02)** where R has the meaning before indicated and X represents a chlorine or bromine atom, isolate the product so formed and convert it into its acid addition salts following the usual procedures. |
| priorityDate | 1978-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.