http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-480053-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 1979-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1980-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-480053-A1 |
| titleOfInvention | A PROCEDURE FOR THE PREPARATION OF NEW QUINAZOLINE DERIVATIVES. |
| abstract | A process for the preparation of new quinazoline derivatives of the formula: ** (Formula-01) ** where R is a lower alkyl group; Y is a group of formula - (CHR1) mZ, where R1 is a hydrogen atom or a lower alkyl group, m is 1 or 2 with the proviso that when m is 2, the R1 groups can be the same or different and Z is a group of formula -N (R2) CONHR5 or -OCNHR5, where R2 is a hydrogen atom or a lower alkyl group and R5 is hydrogen, lower alkyl, benzyl or phenyl; whose procedure is characterized by reacting a quinazoline of formula: ** (Formula-02) ** where R, R1, R2 and m are those defined above, with an isocyanate of formula R5NCO, where R5 is the one defined above but different from hydrogen , or, to prepare compounds where R5 is hydrogen, with sodium or potassium cyanate in the presence of an acid; optionally followed by conversion of the product of formula (I) is a pharmaceutically acceptable acid addition salt by reaction with a non-toxic acid. |
| priorityDate | 1977-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.