abstract |
Procedure for obtaining 1-aryloxy-3-nitratealkylamino-2-propanols of general formula I Ar-O-CH2-CHOH-CH2-NH-R (I) where Ar means phenyl, phenyl one or more times substituted by halogen, cyano, acylamino (where the acyl group has 1-7 carbon atoms) alkanolyl, with 1-4 carbon atoms, alkyl (where the chain may be interrupted by 1 or 2 oxygen atoms or by a sulfur atom and/or where a multiple bond may occur) with a total of 1-10 carbon atoms, cycloalkyl with 3-8 carbon atoms and/or cycloalkoxy with 3-8 carbon atoms; naphthyl, indanyl, indelinyl, tetralyl, indolyl, indolyl substituted by alkyl, in each case with 1-4-carbon atoms, carbazolyl, or 1, 2, 3, 4-tetrahydro-2-oxo.quinolyl and R stands for nitratealkyl with 2-10 carbon atoms and their addition salts. |