http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-476206-A3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a760bf307acddb0484017967033de2b0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- |
filingDate | 1978-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1979-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-476206-A3 |
titleOfInvention | A PREPARATION PROCEDURE IN THE FORM OF BASES OR SALTS OF HETEROCICLIC COMPOUNDS. |
abstract | A process for the preparation, in the form of bases or salts, of heterocyclic compounds of the formula: ** formula ** where R1 represents a halogen atom in position 10 or 11 R2 represents a hydroxyl group and R3 represents a hydrogen atom; or R1 represents a halogen atom in position 10 or 11 and R2 and R3 together form a supplementary bond between the two carbon atoms that carry them, these compounds being in the form of optical isomers or racemic mixtures whose process is characterized by obtain a derivative of formula I where R1 represents a halogen atom R2 represents a hydroxyl group and R3 represents a hydrogen atom by reacting a tabersonine hydrohalogen solution in solution in an alcohol, for 2 to 4 hours, at room temperature and in the presence of a peracid such as m-chloroperbenzoic acid, perphthalic acid or p-nitroperbenzoic acid and to obtain a derivative of formula I where R1 represents a halogen atom and R2 and R3 together form a supplementary bond between the two carbon atoms that carry them , in a classical way by dehydration of a derivative of formula I where R2 and R3 represent respectively a hydroxyl group and a hydrogen atom ene. |
priorityDate | 1978-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.