http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-476168-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 1978-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1979-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-476168-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF NEW IMIDAZO-ISOQUINOLEINDIONAS. |
| abstract | Process for the preparation of new imidazo-isoquinoline-diones of the general formula ** formula ** in which R1 represents a lower alcohol group optionally substituted with a phenyl group, a cycloalkyl group with 3 to 6 carbon atoms or a phenyl group , optionally monosubstituted or disubstituted with halogen atoms, hydroxy, methoxy, methylmercapto, methylsulfinyl, methylsulfonyl and / or benzyloxy groups, the substituents being the same or different, as well as their physiologically compatible acid addition salts, with inorganic or organic acids , characterized in that an 8-nitro-isoquinoline-dione of the general formula ** formula ** and the 8-amino-isoquinoline-dione, formed in situ, of the general formula ** formula ** in which R1 is defined as at the beginning, it is condensed in the presence of an acid condensing agent and, if desired, a compound, obtained according to the invention, of the general formula I, in which R1 represents a group phenyl, which is substituted with a methylmercapto and / or methylsulfinyl group, is transformed by oxidation into a corresponding methylsulfinyl or methylsulfonyl compound of the general formula I and / or a compound obtained of the general formula I, in which R1 represents a phenyl group, which is substituted with a benzyloxy group, by means of debenzylation it is transformed into a corresponding hydroxyl compound of the general formula I and / or a compound obtained from the general formula I is transformed into an acid addition salt physiologically compatible with an inorganic or organic acid. |
| priorityDate | 1977-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.