http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-472702-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-20 |
filingDate | 1978-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1979-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-472702-A1 |
titleOfInvention | A METHOD FOR THE PREPARATION OF NACIL TIENAMICINAS |
abstract | The method of preparation of N-acyl-thienamycins is by reacting the appropriate acyl compound, either as carboxylic acid, amide thereof, peptide thereof or lower alkyl ester thereof with thienamycin either in fermentation broth or in an intermediate state of purity. . Since the resulting derivatives are more susceptible to isolation techniques that employ organic solvents, they allow recovery of the thionamycin nucleus more efficiently from fermentation broths and concentrates. Once the thienamycin derivative is recovered from the broth or solution, the acyl group can be removed in order to regenerate the thienamycin. In the generic representation of the compounds of the present invention, the acyl radical R can be derived from an aliphatic carboxylic acid with more than 5 carbon atoms, saturated or unsaturated, substituted or unsubstituted, aromatic or arylaliphatic carboxylic acid or carbothioic acid. |
priorityDate | 1977-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.